viable lymphocytes in blood products can mediate transfusion associated GVHD
T-Cell
is a usually fatal immunologic transfusion complication
TA-GVHD
and clonal expansion of donor lymphocytes in a susceptible host can cause fatality
Engraftment
is the standard minimum dose used at CHOA to irradiate blood and cellular components
25gy
disease patients must receive irradiated blood products
Hodgkin's
transfusion must be irradiated
Granulocyte
to all neonates and infants 6 months and younger
Transfusions
agent receiving patients receive irradiated blood products
cytotoxic
is used as an alternative to iron chelation therapy
Phlebotomy
is used to manage iron overload
Chelation therapy
is the minimum hgb a patient must have prior to initiating phlebotomy
Seven
should be obtained at baseline and then every 10 minutes during the procedure
Vital signs
should not exceed 10ml/kg to lessen the risk of fluid shift and loss of blood
Phlebotomy
the procedure if falling, blood pressure, decreased cap refill, tachypnea, anxiety, irritability dizziness or pallor
discontinue
MD and start rehydration fluids
notify

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