Chapter 2 Pharmacology Crossword

Originate within the body
A barrier that prevents many substances from entering the CSF
The sequence of chemical steps that convert a drug to a metabolite
Usually be overcome by increasing the dosage of the drug
Cannot be overcome
A state in which a drug cannot be metabolized by a person's body, regardless of the dosage
No clinical response occurs with increased dosage of a drug
A chart displays how a drug reaches a point of no clinical response occurs
First-pass metabolism
An optimal dosage range
When the amount of drug in a patient's blood gives the desired response
The length of time a drug is at therapeutic level
An amount of a drug that will bring the blood concentration rapidly to a therapeutic level
A dose that is calculated by the rate of clearance
A method of mathematically describing the process of ADME of a drug within the body
A fixed quantity of drug is eliminated per unit of time
Depending directly on the concentration of the drugs, a constant fraction
Time it takes the body to eliminate half of such a drug