Hepatitis C Virus Crossword

HCV is a ________ stranded virus1
An organ that is mostly affected by hepatitis C1
Yellow skin1
A late stage of scarring of the liver caused by chronic hepatitis C1
One of the leading causes in liver cancer (abbrev.)1
HCV is spread when someone contact ______ from an infected person1
HCV is a positive sense, ______ virus2
A liver cell, the most frequent site for HCV replication2
The _______ immune system is activated in respond to acute HCV infection1
A consequence of chronic hepatic inflammation that can lead to cirrhosis2
___________ HCV antibody testing means current HCV infection2
The HCV _________ test helps to screen for HCV2
HCV can be _______ and chronic hepatitis4
The viral genomic RNA and the _______ protein form the nucleocapsid4
People who inject ______ are at high risk of HCV infection3
Acute infections are generally __________ or non-specific symptoms1
Sofosbuvir and _________ are the treatment for genotype 2 infection1
There is no vaccine for HCV, but it can be treated and ________2
There are ________known genotypes2
carcinoma is the most common type of primary liver cancer5
There are seven _________, and type 1 is the most prevalent globally5
Direct acting _________ are drugs that can be used to treat hepatitis C4
This is not available for preventing HCV, but it is available to help prevent HAV and HBV infection2
There is a greater affinity for hepatocytes in the liver than other cells2
A protein that inhibits viral replication as a response to HCV infection2
Liver fibrosis is a consequence of chronic hepatic2 __________
___________ infection is when HCV infection last more than 6 months2
Fatigue, myalgia, dark urine, or jaundice6
Muscle pain6
A route of HCV transmission that include blood transfusions and injection drug use2
Coinfection with ______ (abbrev.) and HCV is common because they share a common route of infection6
Chronic hemodialysis and blood transfusions are common routes for percutaneous2
Diagnostic test helps to detect active HCV4 ___________
__________ resistance was reported in patients infected with genotype 1 and 44
A medication that is used to treat HCV, and it is NS5B polymerase inhibitor6
Sofosbuvir can be used to treat HCV, but cannot be used to treat __________6 disease
The most common cause of portal __________ is cirrhosis of the liver 6
_____________ is recommended for all patients with HCV6
A reactive antibody for HCV testing cannot distinguish between ________ and past infection6
The function of IFN- β is to inhibit viral _______ within the affected cells2
When the HCV infection is present, IFN- β promote the production of chemokines and ____________ that activate the adaptive immune system2
The absence of a detectable virus after 12 weeks of therapy (abbrev.)2
Blood samples from ____________ or venepuncture can be used for HCV testing3
Health care workers, injection drug users, and HIV-positive individuals are all considered at high _______ for HCV2
The HCV belongs to the __________ family2
Consumption can exacerbate the pathogenesis of HCV infection7
HCV infection can cause liver ___________. Examples include fibrosis, cirrhosis and HCC7
Small extracellular vesicles that originate from MVE and release to the plasma membrane7
Different _________ cells, such as macrophages, NK cells, and dendritic cells are recruited to the liver in response to HCV7
Cells that are liver residential macrophages7