Drug Metabolism Crossword

Phase 2 reaction where glucuronic acid is transferred to an alcohol, phenol, or other functional group
This herbal supplement induces CYP enzymes
Drug used to treat tuberculosis; highly metabolized by N-acetyltransferases
This group of phase 2 enzymes comes in three types in humans: N,O,S
Name of the P450 enzyme family that contains heme
This type of phase 1 hydrolase deactivates this functional group on proteins, RNA,and DNA
This family of N-acetyltransferases is expressed ubiquitously throughout the body
N-acetyltransferases limit drug-induced toxicities of this type of genetic mutation
This phase inactivates the drug and increases hydrophilicity & molecular weight to promote elimination
This group of phase 2 enzymes transfers a sulfate to substrates and plays a key role in cholesterol and steroid metabolism
Genetic syndrome resulting in higher levels of circulating bilirubin
the better form of glutathione, abbreviated as GSH
This conjugation reaction in phase 2 transfers reactive electrophiles helping the body deal with radicals
This juice inhibits CYP3A4
This phase of metabolism increases hydrophilicity and may or may not inactivate a drug