Human Immunodeficiency Virus Crossword

After _______ infection, acute viremia happens.
This type of reaction happens in HIV immune response
Infection of what kind of cells happen in the bone marrow and thymus lead to reactivation of immune cells?
What cytokines play in regulating HIV expression in tissues?
These cells are part of the initiation of HIV infection in CD4+ T cells
___________ is a way to help prevent HIV infection
What infected humans from primates in the 20th century?
Primary target cells for HIV
What is infected by HIV-1 that are important in pathogenesis in of HIV-1?
What is the active endonuclease in anti-dividing cells?
SAMHD1 has what type of activity that depletes nucleotide cells needed for DNA synthesis?
SAMHD1 restricts HIC-1 reverse _______________
The hypothesis of HIV-1 infection of macrophages doesn't happen in ___________
In what states does the macrophage enter leading to the SAMHD1 activity downregulating?
The downregulated SAMHD1 leads to cells proactive to __________
Retrovirus that does not affect SAMHD1 restriction can infect non-dividing _________ cells.
RNA __________________ help identify subset in alveolar macrophages infected with HIV-1 in vivo.
In vivo, macrophages harbor ______________ HIV infection.
HIV-1 activates innate ___________ responses through PRRs
RNA sensors include: TLR7, RIG-1, and __________
DNA sensors include: cGAS, PQBP1, and ____________
What response influence primary HIV-1 viraemia suppression?
Macrophages stops the HIV response to type- _____ interferon
HIV-1 infection is known as a ___________ inflammatory disease which develops into immunodeficiency.
Correlated with a fast rise in HIV plasma viremia.
Evolution of ___________ responses is the main difference between acute and early HIV infection.
HIV infection of macrophages attenuate __________ and killing via autophagy pathway.
HIV infection can lead to active _____________
TB can increase the levels of HIV ____________.
HIV is one of the ________ leading causes of death around the world.
Transmission ____________ is a set of HIV-1 aggregated sequences in a nonrandom pattern
__________ analysis is a way to identify and breakdown HIV-1 transmission clusters.
Current antiretroviral therapy
Current _____________ therapy suppresses replication of HIV
Current ART regimen includes how many antiretroviral drugs?
A reacting antiretroviral formulation
Parental formulation can help the success rate of preventing the spread of HIV infection. (True or False)
HIV treatment regimens can be limited to one- _______, daily dosing.
Nucleoside reverse transcriptase inhibitors is one of a long-acting antiretroviral ________
HIV affects 36.7 ___________ people all around the world.
Antiretroviral therapy (ART) cannot cure or completely destroy HIV because of the continual latent viral ___________
ART is hard to sustain economically because it is __________.
ART help decrease the risk of infecting the __________ from the mother.
The diversity of HIV has become a problem because the virus _________ are included in different subtypes.
The HIV strain subtypes differ in their _________ proteins.
Neutralizing __________ bind to diverse strains HIV virions and become inactive
BnAb antibodies develop two to hours years ___________ HIV infection.
What is protein is the main target for BnAb antibodies?
What binds to the HIV-1 at gp120 CD4 binding site, having the most human passive immunotherapy?
____________ delivers HIV antigen to the host cell and create immune response.
Vectors are one of the most important parts of a successful ___________.