Clostridium difficile Crossword

Gram positive, anaerobic bacterium in the intestinal tracts of animals and humans
symptoms of CDI include: severe ________, colitis, toxic megacolon, and even death
C. difficile has a ____ homologous recombination rate
genes responsible for virulence factors of C. difficile are found on this element
route of transmission
one of the most significant ___________ infection
drug used to treat CDI
antibiotic for CDI treatment
main barrier against CDI is normal intestinal ________
primary bile salts _________ spore germination
secondary bile salts ________ spore formation
toxin A and toxin B are _________ sequences
PaLoc is transferred by ___________ recombination
type of prevention method
type of genome in C. difficile
C. difficile can remain _________ for a long period of time
The ________ ____ of C. difficile is are 3.2 x 10^-7 mutations per nucleotide per year
type of testing to diagnose CDI
restriction _____ analysis was used for showing strain diversity and transmission
C. difficile typing in North America
Phylum (3)
killer of C. difficile is 1:10 ______
shape of chromosome
drug that can cause CDI
phylogenic kingdom
type of cell wall
growth characteristic
C. difficile contains ___ different clades
______ exposure can lead to increased risk of infection
a higher _____ of antibiotic can cause higher risk of contracting CDI
the rate of _____ by CDI is 1.3% within 30 days of infection
C. diff spores are ______-resistant
size of C. diff genome is 4.3 _____
C. difficile creates ______ in the colon
C. diff has _______ 29,000 people in 2011
the ___ ______ has 947-1033 genes
a new strain of resistant C. diff was caused by a _________ mutation
new resistant strain
third most common transmission of strain in Europe
part of C. diff with lots of protein structures
fecal _______ is the best way to prevent CDI
preventative measure against CDI infection
number of tests to ensure proper diagnosis of CDI
amount of loose stools per day to consider CDI diagnosis
ineffective method of removing C. diff spores
bile acids are converted in this organ
age when CDI risk greatly increases
example of CDI animal model
patients can be ____________ or have severe infection
clade ______ is non-toxigenic